Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
PLG P00747 plasminogen Enzyme 1.0E-02 0.389 0.923
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
KIF7 Q2M1P5 kinesin family member 7 2.3E-22 0.528 0.731
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
MRE11 P49959 MRE11 homolog, double strand break repair nuclease 1.3E-12 0.527 0.808
RAD51C O43502 RAD51 paralog C 6.2E-14 0.533 0.692
NDUFB11 Q9NX14 NADH:ubiquinone oxidoreductase subunit B11 Enzyme 0.80 0.566 0.692
HCCS P53701 holocytochrome c synthase Enzyme 0.89 0.559 0.731
HYLS1 Q96M11 HYLS1 centriolar and ciliogenesis associated 2.3E-09 0.572 0.692
RAD50 Q92878 RAD50 double strand break repair protein 3.4E-27 0.556 0.808
COX7B P24311 cytochrome c oxidase subunit 7B 0.67 0.595 0.654
BARD1 Q99728 BRCA1 associated RING domain 1 1.4E-24 0.597 0.538
RAD51D O75771 RAD51 paralog D 1.1E-09 0.674 0.385