| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
|---|---|---|---|---|---|---|
| BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
| BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
| CHEK2 | O96017 | checkpoint kinase 2 | Kinase | 1.2E-24 | 0.460 | 0.808 |
| MRE11 | P49959 | MRE11 homolog, double strand break repair nuclease | 1.3E-12 | 0.527 | 0.808 | |
| PALB2 | Q86YC2 | partner and localizer of BRCA2 | 3.0E-19 | 0.485 | 0.769 | |
| PLG | P00747 | plasminogen | Enzyme | 1.0E-02 | 0.389 | 0.923 |
| PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
| RAD50 | Q92878 | RAD50 double strand break repair protein | 3.4E-27 | 0.556 | 0.808 | |
| RAD51 | Q06609 | RAD51 recombinase | 2.7E-02 | 0.447 | 0.846 | |
| TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
| WT1 | P19544 | WT1 transcription factor | Nucleic acid binding | 1.00 | 0.422 | 0.808 |