Disease: Down Syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
ACVR1 Q04771 activin A receptor type 1 Kinase 0.33 0.535 0.731
ADAMTS1 Q9UHI8 ADAM metallopeptidase with thrombospondin type 1 motif 1 Enzyme 0.72 0.555 0.654
AIRE O43918 autoimmune regulator 4.0E-12 0.516 0.808
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ARX Q96QS3 aristaless related homeobox 0.91 0.516 0.654
BCAR1 P56945 BCAR1 scaffold protein, Cas family member 1.00 0.518 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CBS P0DN79 P35520 cystathionine beta-synthase Enzyme 3.1E-05 0.465 0.885
CBSL P0DN79 P35520 cystathionine beta-synthase like 0.540 0.808
CDKN1C P49918 cyclin dependent kinase inhibitor 1C 0.82 0.456 0.846
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CDKN2B P42772 cyclin dependent kinase inhibitor 2B 7.3E-03 0.417 0.769
CHDH Q8NE62 choline dehydrogenase Enzyme 1.7E-06 0.529 0.769
CKAP4 Q07065 cytoskeleton associated protein 4 0.51 0.436 0.731
CREB1 P16220 cAMP responsive element binding protein 1 1.00 0.463 0.885
CSE1L P55060 chromosome segregation 1 like Enzyme modulator 1.00 0.521 0.808
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CTNND1 O60716 catenin delta 1 Cellular structure 1.00 0.500 0.808
E2F1 Q01094 E2F transcription factor 1 Nucleic acid binding 0.99 0.441 0.846
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ENOSF1 Q7L5Y1 enolase superfamily member 1 Enzyme 9.0E-19 0.617 0.654