Disease: Plaque, Amyloid
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCA1 O95477 ATP binding cassette subfamily A member 1 Transporter 1.5E-13 0.467 0.846
ABCA7 Q8IZY2 ATP binding cassette subfamily A member 7 Transporter 2.1E-55 0.644 0.577
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
ADAM10 O14672 ADAM metallopeptidase domain 10 1.00 0.489 0.846
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846
AIF1 P55008 allograft inflammatory factor 1 Calcium-binding protein 1.9E-06 0.521 0.808
ALOX5 P09917 arachidonate 5-lipoxygenase Enzyme 1.2E-06 0.447 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
BACE1 P56817 beta-secretase 1 Enzyme 0.88 0.559 0.769
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
C1R P00736 complement C1r Enzyme 0.78 0.638 0.654
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CEBPD P49716 CCAAT enhancer binding protein delta Transcription factor 0.61 0.570 0.769
CHRNA4 P43681 cholinergic receptor nicotinic alpha 4 subunit Ion channel 8.5E-05 0.492 0.808
COL25A1 Q9BXS0 collagen type XXV alpha 1 chain 1.6E-18 0.599 0.538
CST3 P01034 cystatin C 3.9E-03 0.436 0.808
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
CTSK P43235 cathepsin K Enzyme 3.1E-05 0.497 0.808
CTSZ Q9UBR2 cathepsin Z Enzyme 2.3E-16 0.647 0.577
CYP27A1 Q02318 cytochrome P450 family 27 subfamily A member 1 Enzyme 5.3E-19 0.538 0.731