Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
IL10 | P22301 | interleukin 10 | 5.9E-03 | 0.281 | 0.923 | |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
PTGS2 | P35354 | prostaglandin-endoperoxide synthase 2 | Enzyme | 1.00 | 0.314 | 0.962 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
HLA-DRB1 | P01911 | major histocompatibility complex, class II, DR beta 1 | Immune response | 1.1E-03 | 0.333 | 0.923 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
CCND1 | P24385 | cyclin D1 | Enzyme modulator | 0.89 | 0.344 | 0.923 |
EGF | P01133 | epidermal growth factor | 8.5E-17 | 0.357 | 0.923 | |
EPHB2 | P29323 | EPH receptor B2 | Kinase | 1.00 | 0.374 | 0.846 |
NOS2 | P35228 | nitric oxide synthase 2 | 4.0E-15 | 0.364 | 0.923 | |
APC | P25054 | APC regulator of WNT signaling pathway | 1.00 | 0.373 | 0.962 | |
ALK | Q9UM73 | ALK receptor tyrosine kinase | Kinase | 3.2E-06 | 0.396 | 0.846 |
CCL5 | P13501 | C-C motif chemokine ligand 5 | Signaling | 1.8E-03 | 0.403 | 0.885 |
MLH1 | P40692 | mutL homolog 1 | Nucleic acid binding | 3.4E-05 | 0.399 | 0.808 |
MRC1 | P22897 | mannose receptor C-type 1 | 0.94 | 0.413 | 0.846 | |
MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |
SMAD4 | Q13485 | SMAD family member 4 | Transcription factor | 1.00 | 0.401 | 0.808 |
ADRB2 | P07550 | adrenoceptor beta 2 | G-protein coupled receptor | 0.53 | 0.442 | 0.923 |
ARSA | P15289 | arylsulfatase A | Enzyme | 1.1E-11 | 0.448 | 0.923 |
CD36 | P16671 | CD36 molecule | Receptor | 1.1E-60 | 0.446 | 0.846 |
STK11 | Q15831 | serine/threonine kinase 11 | Kinase | 0.99 | 0.435 | 0.808 |