Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
SMUG1 | Q53HV7 | single-strand-selective monofunctional uracil-DNA glycosylase 1 | 4.5E-04 | 0.322 | 0.923 | |
CD274 | Q9NZQ7 | CD274 molecule | Receptor | 1.9E-02 | 0.324 | 0.923 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
AR | P10275 | androgen receptor | Nuclear receptor | 0.99 | 0.351 | 0.846 |
TP63 | Q9H3D4 | tumor protein p63 | Transcription factor | 1.00 | 0.362 | 0.769 |
H3P10 | H3 histone pseudogene 10 | 0.350 | 0.846 | |||
CAV1 | Q03135 | caveolin 1 | Enzyme modulator | 8.3E-03 | 0.388 | 0.885 |
ALK | Q9UM73 | ALK receptor tyrosine kinase | Kinase | 3.2E-06 | 0.396 | 0.846 |
NCAM1 | P13591 | neural cell adhesion molecule 1 | 1.00 | 0.415 | 0.885 | |
STS | P08842 | steroid sulfatase | Enzyme | 0.81 | 0.431 | 0.846 |
CYP1A1 | P04798 | cytochrome P450 family 1 subfamily A member 1 | Enzyme | 1.1E-17 | 0.436 | 0.846 |
MKI67 | P46013 | marker of proliferation Ki-67 | 1.3E-28 | 0.431 | 0.808 | |
HSPA5 | P11021 | heat shock protein family A (Hsp70) member 5 | 0.77 | 0.434 | 0.885 | |
MIB1 | Q86YT6 | mindbomb E3 ubiquitin protein ligase 1 | Enzyme | 3.4E-88 | 0.438 | 0.769 |
NKX2-1 | P43699 | NK2 homeobox 1 | Transcription factor | 0.36 | 0.457 | 0.808 |
PYCARD | Q9ULZ3 | PYD and CARD domain containing | Enzyme | 2.0E-04 | 0.457 | 0.808 |
KRT7 | P08729 | keratin 7 | 3.1E-12 | 0.463 | 0.808 | |
DPYD | Q12882 | dihydropyrimidine dehydrogenase | Enzyme | 3.4E-22 | 0.493 | 0.846 |
XBP1 | P17861 | X-box binding protein 1 | 3.2E-02 | 0.477 | 0.846 | |
NDRG1 | Q92597 | N-myc downstream regulated 1 | Enzyme | 1.1E-02 | 0.488 | 0.731 |