Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 | |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
ALB | P02768 | albumin | Transporter | 0.64 | 0.317 | 0.962 |
SMUG1 | Q53HV7 | single-strand-selective monofunctional uracil-DNA glycosylase 1 | 4.5E-04 | 0.322 | 0.923 | |
CD274 | Q9NZQ7 | CD274 molecule | Receptor | 1.9E-02 | 0.324 | 0.923 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
MYC | P01106 | MYC proto-oncogene, bHLH transcription factor | Transcription factor | 1.00 | 0.344 | 0.923 |
EGF | P01133 | epidermal growth factor | 8.5E-17 | 0.357 | 0.923 | |
H3P10 | H3 histone pseudogene 10 | 0.350 | 0.846 | |||
SMAD4 | Q13485 | SMAD family member 4 | Transcription factor | 1.00 | 0.401 | 0.808 |
ALK | Q9UM73 | ALK receptor tyrosine kinase | Kinase | 3.2E-06 | 0.396 | 0.846 |
GATA3 | P23771 | GATA binding protein 3 | 0.90 | 0.415 | 0.846 | |
CEACAM5 | P06731 | CEA cell adhesion molecule 5 | 4.2E-10 | 0.420 | 0.846 | |
HSPA5 | P11021 | heat shock protein family A (Hsp70) member 5 | 0.77 | 0.434 | 0.885 | |
NKX2-1 | P43699 | NK2 homeobox 1 | Transcription factor | 0.36 | 0.457 | 0.808 |
FOLH1 | Q04609 | folate hydrolase 1 | Enzyme | 6.2E-09 | 0.453 | 0.885 |
UGT1A1 | P22309 | UDP glucuronosyltransferase family 1 member A1 | 3.3E-06 | 0.464 | 0.769 | |
TNFRSF8 | P28908 | TNF receptor superfamily member 8 | 0.86 | 0.444 | 0.808 | |
ZEB2 | O60315 | zinc finger E-box binding homeobox 2 | Transcription factor | 1.00 | 0.471 | 0.808 |
SATB2 | Q9UPW6 | SATB homeobox 2 | Transcription factor | 1.00 | 0.503 | 0.769 |
NTS | P30990 | neurotensin | 3.9E-05 | 0.517 | 0.769 |