Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808
NOTCH2 Q04721 notch receptor 2 1.00 0.441 0.808
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
IDH2 P48735 isocitrate dehydrogenase (NADP(+)) 2 0.88 0.434 0.808
MKI67 P46013 marker of proliferation Ki-67 1.3E-28 0.431 0.808
ERCC1 P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 1.6E-07 0.445 0.846
PSMD9 O00233 proteasome 26S subunit, non-ATPase 9 Enzyme modulator 4.9E-06 0.435 0.846
TMED7 Q86XR7 Q9Y3B3 transmembrane p24 trafficking protein 7 Transporter 0.48 0.436 0.808