Disease: Refractory cancer
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
ABCC3 O15438 ATP binding cassette subfamily C member 3 Transporter 1.2E-26 0.517 0.769
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808
IDH2 P48735 isocitrate dehydrogenase (NADP(+)) 2 0.88 0.434 0.808
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
LRP1 Q07954 LDL receptor related protein 1 1.00 0.482 0.769
MAP2K7 O14733 mitogen-activated protein kinase kinase 7 Kinase 1.00 0.419 0.808
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885
MPRIP Q6WCQ1 myosin phosphatase Rho interacting protein Enzyme modulator 0.98 0.556 0.885
MVP Q14764 major vault protein Nucleic acid binding 6.8E-08 0.512 0.769