Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808
ANGPT2 O15123 angiopoietin 2 Signaling 0.83 0.410 0.846
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885
CDKN2B P42772 cyclin dependent kinase inhibitor 2B 7.3E-03 0.417 0.769
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885
LIG4 P49917 DNA ligase 4 4.2E-06 0.478 0.846
DPYD Q12882 dihydropyrimidine dehydrogenase Enzyme 3.4E-22 0.493 0.846
TCF12 Q99081 transcription factor 12 Transcription factor 0.68 0.565 0.654