Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846
PGR P06401 progesterone receptor Nuclear receptor 5.1E-02 0.426 0.885
CST3 P01034 cystatin C 3.9E-03 0.436 0.808
ROS1 P08922 ROS proto-oncogene 1, receptor tyrosine kinase Kinase 1.6E-72 0.439 0.885
NF2 P35240 neurofibromin 2 1.00 0.468 0.885
BAP1 Q92560 BRCA1 associated protein 1 Enzyme 0.99 0.454 0.731
HES1 Q14469 hes family bHLH transcription factor 1 Transcription factor 0.71 0.468 0.885
CTSL P07711 cathepsin L Enzyme 8.0E-03 0.488 0.846
SMO Q99835 smoothened, frizzled class receptor G-protein coupled receptor 4.3E-07 0.489 0.731
CA2 P00918 carbonic anhydrase 2 1.7E-06 0.506 0.808
CSTB P04080 cystatin B Enzyme modulator 6.6E-03 0.530 0.692
ALAD P13716 aminolevulinate dehydratase Enzyme 5.6E-05 0.556 0.615
TFE3 P19532 transcription factor binding to IGHM enhancer 3 0.98 0.542 0.654
MLLT10 P55197 MLLT10 histone lysine methyltransferase DOT1L cofactor Transcription factor 1.00 0.551 0.462
EHD2 Q9NZN4 EH domain containing 2 Enzyme modulator 0.31 0.760 0.385