Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
CD274 | Q9NZQ7 | CD274 molecule | Receptor | 1.9E-02 | 0.324 | 0.923 |
SPP1 | P10451 | secreted phosphoprotein 1 | 2.1E-06 | 0.353 | 0.885 | |
RET | P07949 | ret proto-oncogene | Kinase | 1.00 | 0.392 | 0.885 |
ALK | Q9UM73 | ALK receptor tyrosine kinase | Kinase | 3.2E-06 | 0.396 | 0.846 |
PGR | P06401 | progesterone receptor | Nuclear receptor | 5.1E-02 | 0.426 | 0.885 |
CST3 | P01034 | cystatin C | 3.9E-03 | 0.436 | 0.808 | |
ROS1 | P08922 | ROS proto-oncogene 1, receptor tyrosine kinase | Kinase | 1.6E-72 | 0.439 | 0.885 |
NF2 | P35240 | neurofibromin 2 | 1.00 | 0.468 | 0.885 | |
BAP1 | Q92560 | BRCA1 associated protein 1 | Enzyme | 0.99 | 0.454 | 0.731 |
HES1 | Q14469 | hes family bHLH transcription factor 1 | Transcription factor | 0.71 | 0.468 | 0.885 |
CTSL | P07711 | cathepsin L | Enzyme | 8.0E-03 | 0.488 | 0.846 |
SMO | Q99835 | smoothened, frizzled class receptor | G-protein coupled receptor | 4.3E-07 | 0.489 | 0.731 |
CA2 | P00918 | carbonic anhydrase 2 | 1.7E-06 | 0.506 | 0.808 | |
CSTB | P04080 | cystatin B | Enzyme modulator | 6.6E-03 | 0.530 | 0.692 |
ALAD | P13716 | aminolevulinate dehydratase | Enzyme | 5.6E-05 | 0.556 | 0.615 |
TFE3 | P19532 | transcription factor binding to IGHM enhancer 3 | 0.98 | 0.542 | 0.654 | |
MLLT10 | P55197 | MLLT10 histone lysine methyltransferase DOT1L cofactor | Transcription factor | 1.00 | 0.551 | 0.462 |
EHD2 | Q9NZN4 | EH domain containing 2 | Enzyme modulator | 0.31 | 0.760 | 0.385 |