Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
VCP | P55072 | valosin containing protein | 1.00 | 0.469 | 0.923 | |
TREM2 | Q9NZC2 | triggering receptor expressed on myeloid cells 2 | 3.3E-09 | 0.519 | 0.769 | |
TMEM106B | Q9NUM4 | transmembrane protein 106B | 0.33 | 0.590 | 0.462 | |
TARDBP | Q13148 | TAR DNA binding protein | 0.99 | 0.493 | 0.808 | |
TBK1 | Q9UHD2 | TANK binding kinase 1 | Kinase | 7.5E-02 | 0.513 | 0.846 |
SNCA | P37840 | synuclein alpha | Transporter | 0.88 | 0.427 | 0.885 |
SOD1 | P00441 | superoxide dismutase 1 | Enzyme | 0.18 | 0.379 | 0.962 |
SLC6A4 | P31645 | solute carrier family 6 member 4 | Transporter | 0.25 | 0.429 | 0.808 |
SLC6A3 | Q01959 | solute carrier family 6 member 3 | Transporter | 1.00 | 0.453 | 0.885 |
SMUG1 | Q53HV7 | single-strand-selective monofunctional uracil-DNA glycosylase 1 | 4.5E-04 | 0.322 | 0.923 | |
SQSTM1 | Q13501 | sequestosome 1 | 8.6E-04 | 0.428 | 0.885 | |
PRKAR1B | P31321 | protein kinase cAMP-dependent type I regulatory subunit beta | 0.18 | 0.716 | 0.385 | |
PRNP | F7VJQ1 P04156 | prion protein | 6.3E-04 | 0.445 | 0.923 | |
PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
MCIDAS | D6RGH6 | multiciliate differentiation and DNA synthesis associated cell cycle protein | 1.3E-02 | 0.566 | 0.769 | |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
LRRK2 | Q5S007 | leucine rich repeat kinase 2 | Kinase | 2.6E-30 | 0.510 | 0.808 |
LAMC2 | Q13753 | laminin subunit gamma 2 | Enzyme modulator | 2.9E-12 | 0.389 | 0.923 |
IGFALS | P35858 | insulin like growth factor binding protein acid labile subunit | Receptor | 5.4E-11 | 0.511 | 0.846 |
HCRT | O43612 | hypocretin neuropeptide precursor | 2.9E-02 | 0.500 | 0.808 | |
GRN | P28799 | granulin precursor | 7.0E-02 | 0.435 | 0.846 | |
FUS | P35637 | FUS RNA binding protein | Nucleic acid binding | 1.00 | 0.470 | 0.846 |
DCTN1 | Q14203 | dynactin subunit 1 | Chaperone | 8.4E-02 | 0.597 | 0.500 |
DNMT1 | P26358 | DNA methyltransferase 1 | Epigenetic regulator | 1.00 | 0.406 | 0.885 |
CSF2 | P04141 | colony stimulating factor 2 | Signaling | 0.83 | 0.330 | 0.962 |