Disease: AMYOTROPHIC LATERAL SCLEROSIS 1
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
NEFL P07196 neurofilament light 0.488 0.769
ZFYVE26 Q68DK2 zinc finger FYVE-type containing 26 4.7E-23 0.636 0.615
OPTN Q96CV9 optineurin 5.9E-18 0.548 0.808
NEFH P12036 neurofilament heavy 2.7E-12 0.588 0.769
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
SARM1 Q6SZW1 sterile alpha and TIR motif containing 1 1.7E-10 0.682 0.346
INA Q16352 internexin neuronal intermediate filament protein alpha 1.5E-08 0.633 0.500
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
CHMP2B Q9UQN3 charged multivesicular body protein 2B 4.6E-06 0.543 0.731
CHCHD10 Q8WYQ3 coiled-coil-helix-coiled-coil-helix domain containing 10 5.4E-06 0.623 0.462
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
CLU P10909 clusterin 7.8E-05 0.426 0.885
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
TBK1 Q9UHD2 TANK binding kinase 1 Kinase 7.5E-02 0.513 0.846
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
TAF15 Q92804 TATA-box binding protein associated factor 15 Nucleic acid binding 0.17 0.626 0.500
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
PFN1 P07737 profilin 1 0.73 0.565 0.769
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
UBQLN2 Q9UHD9 ubiquilin 2 0.85 0.656 0.462
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808
ERBB4 Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 1.00 0.455 0.846
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
HSPA4 P34932 heat shock protein family A (Hsp70) member 4 1.00 0.394 0.923