| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
|---|---|---|---|---|---|---|
| SOD1 | P00441 | superoxide dismutase 1 | Enzyme | 0.18 | 0.379 | 0.962 |
| APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
| SNCA | P37840 | synuclein alpha | Transporter | 0.88 | 0.427 | 0.885 |
| SQSTM1 | Q13501 | sequestosome 1 | 8.6E-04 | 0.428 | 0.885 | |
| GRN | P28799 | granulin precursor | 7.0E-02 | 0.435 | 0.846 | |
| SLC6A3 | Q01959 | solute carrier family 6 member 3 | Transporter | 1.00 | 0.453 | 0.885 |
| ERBB4 | Q15303 | erb-b2 receptor tyrosine kinase 4 | Kinase | 1.00 | 0.455 | 0.846 |
| PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
| VCP | P55072 | valosin containing protein | 1.00 | 0.469 | 0.923 | |
| FUS | P35637 | FUS RNA binding protein | Nucleic acid binding | 1.00 | 0.470 | 0.846 |
| ATXN2 | Q99700 | ataxin 2 | Nucleic acid binding | 0.85 | 0.482 | 0.808 |
| TARDBP | Q13148 | TAR DNA binding protein | 0.99 | 0.493 | 0.808 | |
| C9orf72 | Q96LT7 | C9orf72-SMCR8 complex subunit | 1.1E-06 | 0.496 | 0.769 | |
| HCRT | O43612 | hypocretin neuropeptide precursor | 2.9E-02 | 0.500 | 0.808 | |
| LRRK2 | Q5S007 | leucine rich repeat kinase 2 | Kinase | 2.6E-30 | 0.510 | 0.808 |
| TBK1 | Q9UHD2 | TANK binding kinase 1 | Kinase | 7.5E-02 | 0.513 | 0.846 |
| TREM2 | Q9NZC2 | triggering receptor expressed on myeloid cells 2 | 3.3E-09 | 0.519 | 0.769 | |
| HNRNPA1 | P09651 | heterogeneous nuclear ribonucleoprotein A1 | 1.00 | 0.529 | 0.885 | |
| CHMP2B | Q9UQN3 | charged multivesicular body protein 2B | 4.6E-06 | 0.543 | 0.731 | |
| HTT | P42858 | huntingtin | 1.00 | 0.548 | 0.654 | |
| OPTN | Q96CV9 | optineurin | 5.9E-18 | 0.548 | 0.808 | |
| PSEN2 | P49810 | presenilin 2 | Enzyme | 5.4E-04 | 0.550 | 0.654 |
| PFN1 | P07737 | profilin 1 | 0.73 | 0.565 | 0.769 | |
| NEFH | P12036 | neurofilament heavy | 2.7E-12 | 0.588 | 0.769 | |
| TOMM40 | O96008 | translocase of outer mitochondrial membrane 40 | Transporter | 0.99 | 0.590 | 0.538 |