Disease: Alzheimer Disease, Late Onset
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
STH Q8IWL8 saitohin 0.705 0.385
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
POLD1 P28340 DNA polymerase delta 1, catalytic subunit 2.4E-06 0.507 0.769
CHI3L1 P36222 chitinase 3 like 1 1.1E-05 0.419 0.885
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
CRHR1 P34998 corticotropin releasing hormone receptor 1 3.8E-05 0.517 0.769
CLU P10909 clusterin 7.8E-05 0.426 0.885
SLC25A27 O95847 solute carrier family 25 member 27 Transporter 2.7E-04 0.711 0.423
PSEN2 P49810 presenilin 2 Enzyme 5.4E-04 0.550 0.654
APOD P05090 apolipoprotein D 5.4E-04 0.584 0.577
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
SUCLA2 Q9P2R7 succinate-CoA ligase ADP-forming subunit beta Enzyme 2.3E-03 0.566 0.654
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
PYY P10082 peptide YY Signaling 1.2E-02 0.588 0.615