Disease: Mental deterioration
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MFSD8 Q8NHS3 major facilitator superfamily domain containing 8 2.5E-12 0.682 0.231
STH Q8IWL8 saitohin 0.705 0.385
CALCOCO2 Q13137 calcium binding and coiled-coil domain 2 1.0E-04 0.722 0.423
UBQLN2 Q9UHD9 ubiquilin 2 0.85 0.656 0.462
TMEM106B Q9NUM4 transmembrane protein 106B 0.33 0.590 0.462
GABRB2 P47870 gamma-aminobutyric acid type A receptor subunit beta2 Ion channel 0.85 0.619 0.500
AARS2 Q5JTZ9 alanyl-tRNA synthetase 2, mitochondrial Nucleic acid binding 5.0E-17 0.644 0.500
PICALM Q13492 phosphatidylinositol binding clathrin assembly protein Transporter 1.00 0.592 0.538
TOMM40 O96008 translocase of outer mitochondrial membrane 40 Transporter 0.99 0.590 0.538
SPG11 Q96JI7 SPG11 vesicle trafficking associated, spatacsin 1.6E-39 0.576 0.538
NRGN Q92686 neurogranin 0.48 0.608 0.615
HTT P42858 huntingtin 1.00 0.548 0.654
PSEN2 P49810 presenilin 2 Enzyme 5.4E-04 0.550 0.654
SUCLA2 Q9P2R7 succinate-CoA ligase ADP-forming subunit beta Enzyme 2.3E-03 0.566 0.654
SRRM2 Q9UQ35 serine/arginine repetitive matrix 2 1.00 0.564 0.692
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769
MEF2C Q06413 myocyte enhancer factor 2C Transcription factor 1.7E-02 0.517 0.769
NEFL P07196 neurofilament light 0.488 0.769
PSPN O60542 persephin Signaling 1.1E-04 0.608 0.769
PTBP1 P26599 polypyrimidine tract binding protein 1 1.00 0.517 0.769
STXBP3 O00186 syntaxin binding protein 3 Transporter 5.2E-05 0.610 0.769
RIDA P52758 reactive intermediate imine deaminase A homolog 6.8E-02 0.606 0.769
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
MCIDAS D6RGH6 multiciliate differentiation and DNA synthesis associated cell cycle protein 1.3E-02 0.566 0.769