Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
ACE | P12821 | angiotensin I converting enzyme | Enzyme | 1.0E-37 | 0.328 | 0.923 |
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
ATXN2 | Q99700 | ataxin 2 | Nucleic acid binding | 0.85 | 0.482 | 0.808 |
BNIP1 | Q12981 | BCL2 interacting protein 1 | 9.7E-07 | 0.792 | 0.346 | |
BPIFA2 | Q96DR5 | BPI fold containing family A member 2 | 8.0E-07 | 0.608 | 0.808 | |
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
C9orf72 | Q96LT7 | C9orf72-SMCR8 complex subunit | 1.1E-06 | 0.496 | 0.769 | |
CASP3 | P42574 | caspase 3 | Enzyme | 0.10 | 0.351 | 0.923 |
CBS | P0DN79 P35520 | cystathionine beta-synthase | Enzyme | 3.1E-05 | 0.465 | 0.885 |
CDK5 | Q00535 | cyclin dependent kinase 5 | Kinase | 0.14 | 0.495 | 0.846 |
CHI3L1 | P36222 | chitinase 3 like 1 | 1.1E-05 | 0.419 | 0.885 | |
CIT | O14578 | citron rho-interacting serine/threonine kinase | Kinase | 1.00 | 0.555 | 0.692 |
CLU | P10909 | clusterin | 7.8E-05 | 0.426 | 0.885 | |
CRHR1 | P34998 | corticotropin releasing hormone receptor 1 | 3.8E-05 | 0.517 | 0.769 | |
CSF2 | P04141 | colony stimulating factor 2 | Signaling | 0.83 | 0.330 | 0.962 |
CYP2D6 | P10635 | cytochrome P450 family 2 subfamily D member 6 | 1.1E-25 | 0.437 | 0.885 | |
DCTN1 | Q14203 | dynactin subunit 1 | Chaperone | 8.4E-02 | 0.597 | 0.500 |
EIF2AK3 | Q9NZJ5 | eukaryotic translation initiation factor 2 alpha kinase 3 | Kinase | 2.8E-03 | 0.501 | 0.808 |
ERBB4 | Q15303 | erb-b2 receptor tyrosine kinase 4 | Kinase | 1.00 | 0.455 | 0.846 |
FMR1 | Q06787 | FMRP translational regulator 1 | Nucleic acid binding | 0.65 | 0.473 | 0.769 |
FUS | P35637 | FUS RNA binding protein | Nucleic acid binding | 1.00 | 0.470 | 0.846 |
GFAP | P14136 | glial fibrillary acidic protein | 1.5E-06 | 0.421 | 0.885 | |
GLDC | P23378 | glycine decarboxylase | Enzyme | 6.6E-28 | 0.628 | 0.577 |
GRN | P28799 | granulin precursor | 7.0E-02 | 0.435 | 0.846 |