Disease: Motor Neuron Disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AAAS Q9NRG9 aladin WD repeat nucleoporin 2.4E-13 0.601 0.654
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CDK5 Q00535 cyclin dependent kinase 5 Kinase 0.14 0.495 0.846
CDK5R1 Q15078 cyclin dependent kinase 5 regulatory subunit 1 Enzyme modulator 0.91 0.529 0.808
CHCHD10 Q8WYQ3 coiled-coil-helix-coiled-coil-helix domain containing 10 5.4E-06 0.623 0.462
CHCHD2 Q9Y6H1 coiled-coil-helix-coiled-coil-helix domain containing 2 1.7E-07 0.638 0.538
CHMP2B Q9UQN3 charged multivesicular body protein 2B 4.6E-06 0.543 0.731
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
DCTN4 Q9UJW0 dynactin subunit 4 0.73 0.472 0.846
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885
EIF2AK3 Q9NZJ5 eukaryotic translation initiation factor 2 alpha kinase 3 Kinase 2.8E-03 0.501 0.808
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
GAP43 P17677 growth associated protein 43 2.1E-02 0.564 0.731
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
GTF2H1 P32780 general transcription factor IIH subunit 1 Transcription factor 0.99 0.469 0.846
HNRNPA2B1 P22626 heterogeneous nuclear ribonucleoprotein A2/B1 1.00 0.566 0.808
HRES1 P13985 HTLV-1 related endogenous sequence 0.636 0.615
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
KHDRBS1 Q07666 KH RNA binding domain containing, signal transduction associated 1 Nucleic acid binding 0.99 0.457 0.846