Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ADAMTS2 O95450 ADAM metallopeptidase with thrombospondin type 1 motif 2 Enzyme 0.97 0.579 0.808
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
CTSC P53634 cathepsin C Enzyme 1.1E-07 0.541 0.731
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769
HTT P42858 huntingtin 1.00 0.548 0.654
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
NEFL P07196 neurofilament light 0.488 0.769
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
PFN1 P07737 profilin 1 0.73 0.565 0.769
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
SNAP25 P60880 synaptosome associated protein 25 Transporter 0.99 0.489 0.808
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SPTLC1 O15269 serine palmitoyltransferase long chain base subunit 1 Enzyme 4.2E-11 0.650 0.538
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962