Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
ADAMTS2 | O95450 | ADAM metallopeptidase with thrombospondin type 1 motif 2 | Enzyme | 0.97 | 0.579 | 0.808 |
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
CSF2 | P04141 | colony stimulating factor 2 | Signaling | 0.83 | 0.330 | 0.962 |
CTSC | P53634 | cathepsin C | Enzyme | 1.1E-07 | 0.541 | 0.731 |
FMR1 | Q06787 | FMRP translational regulator 1 | Nucleic acid binding | 0.65 | 0.473 | 0.769 |
HTT | P42858 | huntingtin | 1.00 | 0.548 | 0.654 | |
IGFALS | P35858 | insulin like growth factor binding protein acid labile subunit | Receptor | 5.4E-11 | 0.511 | 0.846 |
LAMC2 | Q13753 | laminin subunit gamma 2 | Enzyme modulator | 2.9E-12 | 0.389 | 0.923 |
LRRK2 | Q5S007 | leucine rich repeat kinase 2 | Kinase | 2.6E-30 | 0.510 | 0.808 |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
NEFL | P07196 | neurofilament light | 0.488 | 0.769 | ||
NOS2 | P35228 | nitric oxide synthase 2 | 4.0E-15 | 0.364 | 0.923 | |
PFN1 | P07737 | profilin 1 | 0.73 | 0.565 | 0.769 | |
PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
SLC6A3 | Q01959 | solute carrier family 6 member 3 | Transporter | 1.00 | 0.453 | 0.885 |
SMUG1 | Q53HV7 | single-strand-selective monofunctional uracil-DNA glycosylase 1 | 4.5E-04 | 0.322 | 0.923 | |
SNAP25 | P60880 | synaptosome associated protein 25 | Transporter | 0.99 | 0.489 | 0.808 |
SNCA | P37840 | synuclein alpha | Transporter | 0.88 | 0.427 | 0.885 |
SOD1 | P00441 | superoxide dismutase 1 | Enzyme | 0.18 | 0.379 | 0.962 |
SPTLC1 | O15269 | serine palmitoyltransferase long chain base subunit 1 | Enzyme | 4.2E-11 | 0.650 | 0.538 |
TARDBP | Q13148 | TAR DNA binding protein | 0.99 | 0.493 | 0.808 | |
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |