Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
ACE | P12821 | angiotensin I converting enzyme | Enzyme | 1.0E-37 | 0.328 | 0.923 |
ACHE | P22303 | acetylcholinesterase (Cartwright blood group) | Enzyme | 1.00 | 0.445 | 0.885 |
APOC1 | P02654 | apolipoprotein C1 | 0.22 | 0.581 | 0.577 | |
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
ATP5F1A | P25705 | ATP synthase F1 subunit alpha | Transporter | 1.00 | 0.604 | 0.731 |
BCHE | P06276 | butyrylcholinesterase | 1.1E-13 | 0.447 | 0.923 | |
C9orf72 | Q96LT7 | C9orf72-SMCR8 complex subunit | 1.1E-06 | 0.496 | 0.769 | |
CASP3 | P42574 | caspase 3 | Enzyme | 0.10 | 0.351 | 0.923 |
CDK5 | Q00535 | cyclin dependent kinase 5 | Kinase | 0.14 | 0.495 | 0.846 |
CDK5R1 | Q15078 | cyclin dependent kinase 5 regulatory subunit 1 | Enzyme modulator | 0.91 | 0.529 | 0.808 |
CLU | P10909 | clusterin | 7.8E-05 | 0.426 | 0.885 | |
CSF2 | P04141 | colony stimulating factor 2 | Signaling | 0.83 | 0.330 | 0.962 |
CYP2D6 | P10635 | cytochrome P450 family 2 subfamily D member 6 | 1.1E-25 | 0.437 | 0.885 | |
DAPK1 | P53355 | death associated protein kinase 1 | Kinase | 1.00 | 0.472 | 0.808 |
DPP6 | P42658 | dipeptidyl peptidase like 6 | Enzyme | 0.34 | 0.603 | 0.692 |
GSK3B | P49841 | glycogen synthase kinase 3 beta | Kinase | 0.96 | 0.430 | 0.846 |
HTT | P42858 | huntingtin | 1.00 | 0.548 | 0.654 | |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
LAMC2 | Q13753 | laminin subunit gamma 2 | Enzyme modulator | 2.9E-12 | 0.389 | 0.923 |
LEP | P41159 | leptin | 0.46 | 0.349 | 0.846 | |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
MMP2 | P08253 | matrix metallopeptidase 2 | Enzyme | 0.84 | 0.333 | 0.923 |
NPY | P01303 | neuropeptide Y | Signaling | 0.14 | 0.447 | 0.846 |
PICALM | Q13492 | phosphatidylinositol binding clathrin assembly protein | Transporter | 1.00 | 0.592 | 0.538 |