Disease: Frontotemporal Lobar Degeneration
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
BPIFA2 Q96DR5 BPI fold containing family A member 2 8.0E-07 0.608 0.808
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CDC7 O00311 cell division cycle 7 Kinase 4.4E-06 0.641 0.462
CDK5R1 Q15078 cyclin dependent kinase 5 regulatory subunit 1 Enzyme modulator 0.91 0.529 0.808
CHI3L1 P36222 chitinase 3 like 1 1.1E-05 0.419 0.885
CHIT1 Q13231 chitinase 1 7.2E-16 0.525 0.692
CHMP2B Q9UQN3 charged multivesicular body protein 2B 4.6E-06 0.543 0.731
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
DCTN4 Q9UJW0 dynactin subunit 4 0.73 0.472 0.846
DCUN1D1 Q96GG9 defective in cullin neddylation 1 domain containing 1 0.99 0.670 0.538
EWSR1 Q01844 EWS RNA binding protein 1 Nucleic acid binding 1.00 0.474 0.692
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
GFRA2 O00451 GDNF family receptor alpha 2 9.8E-02 0.716 0.423
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
GTF2H1 P32780 general transcription factor IIH subunit 1 Transcription factor 0.99 0.469 0.846
HCRT O43612 hypocretin neuropeptide precursor 2.9E-02 0.500 0.808
HMBS P08397 hydroxymethylbilane synthase Enzyme 0.95 0.559 0.731
HNRNPA1 P09651 heterogeneous nuclear ribonucleoprotein A1 1.00 0.529 0.885
HNRNPA1P10 heterogeneous nuclear ribonucleoprotein A1 pseudogene 10 0.631 0.654