Disease: Tauopathies
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
BPIFA2 Q96DR5 BPI fold containing family A member 2 8.0E-07 0.608 0.808
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CASP2 P42575 caspase 2 Enzyme 1.5E-03 0.565 0.731
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CDK5 Q00535 cyclin dependent kinase 5 Kinase 0.14 0.495 0.846
CHI3L1 P36222 chitinase 3 like 1 1.1E-05 0.419 0.885
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
DCTN4 Q9UJW0 dynactin subunit 4 0.73 0.472 0.846
EIF2AK3 Q9NZJ5 eukaryotic translation initiation factor 2 alpha kinase 3 Kinase 2.8E-03 0.501 0.808
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846
GTF2H1 P32780 general transcription factor IIH subunit 1 Transcription factor 0.99 0.469 0.846
HSPA4 P34932 heat shock protein family A (Hsp70) member 4 1.00 0.394 0.923
HTT P42858 huntingtin 1.00 0.548 0.654
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
KHDRBS1 Q07666 KH RNA binding domain containing, signal transduction associated 1 Nucleic acid binding 0.99 0.457 0.846
LEP P41159 leptin 0.46 0.349 0.846