Disease: Degenerative disorder
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
ATG7 O95352 autophagy related 7 Enzyme 7.4E-12 0.505 0.769
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923
CFDP1 Q9UEE9 craniofacial development protein 1 3.7E-03 0.619 0.615
CHI3L1 P36222 chitinase 3 like 1 1.1E-05 0.419 0.885
CHIT1 Q13231 chitinase 1 7.2E-16 0.525 0.692
DCTN4 Q9UJW0 dynactin subunit 4 0.73 0.472 0.846
EIF4G2 P78344 eukaryotic translation initiation factor 4 gamma 2 Nucleic acid binding 1.00 0.593 0.692
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
GEMIN4 P57678 gem nuclear organelle associated protein 4 5.9E-13 0.565 0.808
GTF2H1 P32780 general transcription factor IIH subunit 1 Transcription factor 0.99 0.469 0.846
HTT P42858 huntingtin 1.00 0.548 0.654
KHDRBS1 Q07666 KH RNA binding domain containing, signal transduction associated 1 Nucleic acid binding 0.99 0.457 0.846
LMNA P02545 lamin A/C 1.00 0.384 0.885
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
MFSD8 Q8NHS3 major facilitator superfamily domain containing 8 2.5E-12 0.682 0.231
NOTCH3 Q9UM47 notch receptor 3 0.41 0.435 0.808
NUP62 P37198 nucleoporin 62 Transporter 0.95 0.470 0.885
PGF P49763 placental growth factor Signaling 0.13 0.460 0.846
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
PSMD2 Q13200 proteasome 26S subunit, non-ATPase 2 Enzyme modulator 1.00 0.612 0.692
RIPK1 Q13546 receptor interacting serine/threonine kinase 1 Kinase 7.9E-03 0.479 0.769