Disease: Amyotrophic Lateral Sclerosis, Sporadic
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ADARB1 P78563 adenosine deaminase RNA specific B1 Enzyme 0.80 0.588 0.654
APEX1 P27695 apurinic/apyrimidinic endodeoxyribonuclease 1 1.9E-07 0.458 0.846
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CCNF P41002 cyclin F Enzyme modulator 0.13 0.700 0.615
CHI3L1 P36222 chitinase 3 like 1 1.1E-05 0.419 0.885
CLU P10909 clusterin 7.8E-05 0.426 0.885
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
CYP27A1 Q02318 cytochrome P450 family 27 subfamily A member 1 Enzyme 5.3E-19 0.538 0.731
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
DPP6 P42658 dipeptidyl peptidase like 6 Enzyme 0.34 0.603 0.692
ERBB4 Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 1.00 0.455 0.846
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
GRIA3 P42263 glutamate ionotropic receptor AMPA type subunit 3 Ion channel 1.00 0.566 0.692
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
INA Q16352 internexin neuronal intermediate filament protein alpha 1.5E-08 0.633 0.500
MAK16 Q9BXY0 MAK16 homolog 0.96 0.566 0.615
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
MATR3 P43243 matrin 3 1.00 0.631 0.538
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
NEFH P12036 neurofilament heavy 2.7E-12 0.588 0.769
NUP98 P52948 nucleoporin 98 and 96 precursor Enzyme 1.00 0.532 0.577