Disease: TDP-43 Proteinopathies
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CAMK2A Q9UQM7 calcium/calmodulin dependent protein kinase II alpha Kinase 1.00 0.612 0.538
CDC7 O00311 cell division cycle 7 Kinase 4.4E-06 0.641 0.462
CHMP2B Q9UQN3 charged multivesicular body protein 2B 4.6E-06 0.543 0.731
CSNK1D P48730 casein kinase 1 delta Kinase 1.00 0.650 0.615
DCTN4 Q9UJW0 dynactin subunit 4 0.73 0.472 0.846
GLCE O94923 glucuronic acid epimerase 0.65 0.729 0.269
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
GTF2H1 P32780 general transcription factor IIH subunit 1 Transcription factor 0.99 0.469 0.846
HTT P42858 huntingtin 1.00 0.548 0.654
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
KHDRBS1 Q07666 KH RNA binding domain containing, signal transduction associated 1 Nucleic acid binding 0.99 0.457 0.846
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
NUP62 P37198 nucleoporin 62 Transporter 0.95 0.470 0.885
PABPN1 Q86U42 poly(A) binding protein nuclear 1 0.39 0.674 0.423
RRM1 P23921 ribonucleotide reductase catalytic subunit M1 Enzyme 1.00 0.552 0.692
SIGMAR1 Q99720 sigma non-opioid intracellular receptor 1 0.17 0.544 0.808
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808
TMEM106B Q9NUM4 transmembrane protein 106B 0.33 0.590 0.462