Disease: GRN-related frontotemporal dementia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
BPIFA2 Q96DR5 BPI fold containing family A member 2 8.0E-07 0.608 0.808
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CDC7 O00311 cell division cycle 7 Kinase 4.4E-06 0.641 0.462
CHMP2B Q9UQN3 charged multivesicular body protein 2B 4.6E-06 0.543 0.731
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
DCTN4 Q9UJW0 dynactin subunit 4 0.73 0.472 0.846
DCUN1D1 Q96GG9 defective in cullin neddylation 1 domain containing 1 0.99 0.670 0.538
EWSR1 Q01844 EWS RNA binding protein 1 Nucleic acid binding 1.00 0.474 0.692
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
GTF2H1 P32780 general transcription factor IIH subunit 1 Transcription factor 0.99 0.469 0.846
HCRT O43612 hypocretin neuropeptide precursor 2.9E-02 0.500 0.808
HNRNPA1 P09651 heterogeneous nuclear ribonucleoprotein A1 1.00 0.529 0.885
HNRNPA1P10 heterogeneous nuclear ribonucleoprotein A1 pseudogene 10 0.631 0.654
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
INA Q16352 internexin neuronal intermediate filament protein alpha 1.5E-08 0.633 0.500
KHDRBS1 Q07666 KH RNA binding domain containing, signal transduction associated 1 Nucleic acid binding 0.99 0.457 0.846
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
MAK16 Q9BXY0 MAK16 homolog 0.96 0.566 0.615
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
MATR3 P43243 matrin 3 1.00 0.631 0.538