Disease: Motor neuron atrophy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APEX1 P27695 apurinic/apyrimidinic endodeoxyribonuclease 1 1.9E-07 0.458 0.846
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CDK5 Q00535 cyclin dependent kinase 5 Kinase 0.14 0.495 0.846
CHIT1 Q13231 chitinase 1 7.2E-16 0.525 0.692
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
DCTN4 Q9UJW0 dynactin subunit 4 0.73 0.472 0.846
DDX3X O00571 DEAD-box helicase 3 X-linked 1.00 0.537 0.769
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885
ERBB4 Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 1.00 0.455 0.846
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846
GTF2H1 P32780 general transcription factor IIH subunit 1 Transcription factor 0.99 0.469 0.846
HNRNPA1 P09651 heterogeneous nuclear ribonucleoprotein A1 1.00 0.529 0.885
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
KHDRBS1 Q07666 KH RNA binding domain containing, signal transduction associated 1 Nucleic acid binding 0.99 0.457 0.846
MAP4K4 O95819 mitogen-activated protein kinase kinase kinase kinase 4 Kinase 1.00 0.588 0.692
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
NEFH P12036 neurofilament heavy 2.7E-12 0.588 0.769
NEFL P07196 neurofilament light 0.488 0.769
NUP62 P37198 nucleoporin 62 Transporter 0.95 0.470 0.885
OPTN Q96CV9 optineurin 5.9E-18 0.548 0.808
PFN1 P07737 profilin 1 0.73 0.565 0.769
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923