Disease: Sporadic Parkinson disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
APEX1 P27695 apurinic/apyrimidinic endodeoxyribonuclease 1 1.9E-07 0.458 0.846
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
ATG7 O95352 autophagy related 7 Enzyme 7.4E-12 0.505 0.769
CDK5 Q00535 cyclin dependent kinase 5 Kinase 0.14 0.495 0.846
CHCHD2 Q9Y6H1 coiled-coil-helix-coiled-coil-helix domain containing 2 1.7E-07 0.638 0.538
CSNK1D P48730 casein kinase 1 delta Kinase 1.00 0.650 0.615
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
HSPA4 P34932 heat shock protein family A (Hsp70) member 4 1.00 0.394 0.923
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
MAPK8 P45983 mitogen-activated protein kinase 8 Kinase 1.00 0.397 0.885
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923