Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCA7 Q8IZY2 ATP binding cassette subfamily A member 7 Transporter 2.1E-55 0.644 0.577
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CHMP2B Q9UQN3 charged multivesicular body protein 2B 4.6E-06 0.543 0.731
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
NEFL P07196 neurofilament light 0.488 0.769
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
PCBP2 Q15366 poly(rC) binding protein 2 Enzyme 1.00 0.647 0.577
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
PSEN2 P49810 presenilin 2 Enzyme 5.4E-04 0.550 0.654
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
SORL1 Q92673 sortilin related receptor 1 Transporter 7.7E-11 0.582 0.692
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808
TMEM106B Q9NUM4 transmembrane protein 106B 0.33 0.590 0.462
TOMM40 O96008 translocase of outer mitochondrial membrane 40 Transporter 0.99 0.590 0.538
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769