Disease: MAJOR AFFECTIVE DISORDER 9
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846
ADRB2 P07550 adrenoceptor beta 2 G-protein coupled receptor 0.53 0.442 0.923
P2RX7 Q99572 purinergic receptor P2X 7 Ion channel 3.3E-11 0.450 0.808
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
CLOCK O15516 clock circadian regulator 1.00 0.463 0.885
NRG1 Q02297 neuregulin 1 Signaling 1.00 0.464 0.885
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
GAD1 Q99259 glutamate decarboxylase 1 Enzyme 4.6E-02 0.486 0.885
CACNA1C Q13936 calcium voltage-gated channel subunit alpha1 C Ion channel 1.00 0.510 0.846
NR1H4 Q96RI1 nuclear receptor subfamily 1 group H member 4 Nuclear receptor 9.4E-04 0.513 0.808
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808
TRPM2 O94759 transient receptor potential cation channel subfamily M member 2 Ion channel 9.0E-44 0.546 0.731
DISC1 Q9NRI5 DISC1 scaffold protein 1.7E-06 0.548 0.769
SHANK3 Q9BYB0 SH3 and multiple ankyrin repeat domains 3 1.00 0.550 0.731
ANK3 Q12955 ankyrin 3 1.00 0.578 0.654
DTNBP1 Q96EV8 dystrobrevin binding protein 1 6.8E-06 0.588 0.615
DRD5 P21918 dopamine receptor D5 G-protein coupled receptor 1.3E-16 0.603 0.423
GRK3 P35626 G protein-coupled receptor kinase 3 Kinase 0.71 0.621 0.731