Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 | |
IFNG | P01579 | interferon gamma | 0.47 | 0.288 | 0.962 | |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
CRP | P02741 | C-reactive protein | 3.7E-03 | 0.299 | 0.962 | |
MMP9 | P14780 | matrix metallopeptidase 9 | Enzyme | 1.9E-17 | 0.305 | 0.923 |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
TLR4 | O00206 | toll like receptor 4 | 4.6E-09 | 0.321 | 0.962 | |
CCL2 | P13500 | C-C motif chemokine ligand 2 | Signaling | 0.61 | 0.321 | 0.962 |
PIK3CD | O00329 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | Kinase | 1.00 | 0.319 | 0.885 |
PIK3CG | P48736 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | Kinase | 1.4E-06 | 0.320 | 0.885 |
PIK3CB | P42338 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta | Kinase | 1.00 | 0.322 | 0.885 |
MMP2 | P08253 | matrix metallopeptidase 2 | Enzyme | 0.84 | 0.333 | 0.923 |
BDNF | P23560 | brain derived neurotrophic factor | Signaling | 0.66 | 0.345 | 0.923 |
MTHFR | P42898 | methylenetetrahydrofolate reductase | 3.2E-10 | 0.337 | 0.885 | |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
ABCB1 | P08183 | ATP binding cassette subfamily B member 1 | Transporter | 1.3E-05 | 0.344 | 0.885 |
POMC | P01189 | proopiomelanocortin | 1.2E-04 | 0.356 | 0.846 | |
NOS2 | P35228 | nitric oxide synthase 2 | 4.0E-15 | 0.364 | 0.923 | |
EGF | P01133 | epidermal growth factor | 8.5E-17 | 0.357 | 0.923 | |
TLR2 | O60603 | toll like receptor 2 | 1.0E-06 | 0.361 | 0.923 | |
TERT | O14746 | telomerase reverse transcriptase | Enzyme | 0.99 | 0.374 | 0.846 |
IL1RN | P18510 | interleukin 1 receptor antagonist | 3.1E-02 | 0.373 | 0.923 | |
NOTCH1 | P46531 | notch receptor 1 | 1.00 | 0.369 | 0.885 |