Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
HIF1A | Q16665 | hypoxia inducible factor 1 subunit alpha | Transcription factor | 0.98 | 0.327 | 0.923 |
CD274 | Q9NZQ7 | CD274 molecule | Receptor | 1.9E-02 | 0.324 | 0.923 |
CCND1 | P24385 | cyclin D1 | Enzyme modulator | 0.89 | 0.344 | 0.923 |
VDR | P11473 | vitamin D receptor | Nuclear receptor | 1.7E-05 | 0.352 | 0.885 |
TP63 | Q9H3D4 | tumor protein p63 | Transcription factor | 1.00 | 0.362 | 0.769 |
MDM2 | Q00987 | MDM2 proto-oncogene | Nucleic acid binding | 1.00 | 0.362 | 0.846 |
NOTCH1 | P46531 | notch receptor 1 | 1.00 | 0.369 | 0.885 | |
RET | P07949 | ret proto-oncogene | Kinase | 1.00 | 0.392 | 0.885 |
PTCH1 | Q13635 | patched 1 | 1.00 | 0.398 | 0.885 | |
MMP1 | P03956 | matrix metallopeptidase 1 | Enzyme | 7.7E-18 | 0.385 | 0.885 |
PCNA | P12004 | proliferating cell nuclear antigen | Nucleic acid binding | 0.98 | 0.382 | 0.846 |
CDKN1A | P38936 | cyclin dependent kinase inhibitor 1A | 1.9E-03 | 0.403 | 0.769 | |
MME | P08473 | membrane metalloendopeptidase | Enzyme | 1.5E-18 | 0.407 | 0.808 |
RPE65 | Q16518 | retinoid isomerohydrolase RPE65 | Enzyme | 6.5E-14 | 0.417 | 0.808 |
BMP4 | P12644 | bone morphogenetic protein 4 | Signaling | 0.96 | 0.422 | 0.808 |
HSPG2 | P98160 | heparan sulfate proteoglycan 2 | Enzyme modulator | 1.0E-19 | 0.438 | 0.885 |
GLI3 | P10071 | GLI family zinc finger 3 | 1.00 | 0.436 | 0.846 | |
GLI1 | P08151 | GLI family zinc finger 1 | 7.7E-14 | 0.431 | 0.846 | |
GLI2 | P10070 | GLI family zinc finger 2 | 0.97 | 0.446 | 0.846 | |
MKI67 | P46013 | marker of proliferation Ki-67 | 1.3E-28 | 0.431 | 0.808 | |
PSMD9 | O00233 | proteasome 26S subunit, non-ATPase 9 | Enzyme modulator | 4.9E-06 | 0.435 | 0.846 |