Disease: TNF receptor-associated periodic fever syndrome (TRAPS)
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CGA P01215 glycoprotein hormones, alpha polypeptide 0.35 0.508 0.808
CUX1 P39880 Q13948 cut like homeobox 1 Transcription factor 1.00 0.465 0.846
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
CYP17A1 P05093 cytochrome P450 family 17 subfamily A member 1 2.6E-04 0.462 0.769
GORASP1 Q9BQQ3 golgi reassembly stacking protein 1 2.0E-02 0.428 0.846
HCLS1 P14317 hematopoietic cell-specific Lyn substrate 1 Cellular structure 1.3E-06 0.539 0.846
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL2RB P14784 interleukin 2 receptor subunit beta Receptor 0.29 0.491 0.846
IL6 P05231 interleukin 6 0.32 0.248 0.962
KHSRP Q92945 KH-type splicing regulatory protein Enzyme 1.00 0.526 0.846
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PSIP1 O75475 PC4 and SFRS1 interacting protein 1 Signaling 1.00 0.490 0.846
RELA Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 1.00 0.406 0.885
SIGLEC7 Q9Y286 sialic acid binding Ig like lectin 7 Receptor 2.4E-07 0.535 0.846
SYT1 P21579 synaptotagmin 1 Transporter 0.60 0.412 0.846
TCF3 P15923 transcription factor 3 Transcription factor 2.6E-02 0.476 0.846
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962