Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
IL1B | P01584 | interleukin 1 beta | 0.13 | 0.276 | 0.962 | |
IFNG | P01579 | interferon gamma | 0.47 | 0.288 | 0.962 | |
IL1A | P01583 | interleukin 1 alpha | 1.6E-04 | 0.333 | 0.962 | |
NLRP3 | Q96P20 | NLR family pyrin domain containing 3 | 8.1E-04 | 0.361 | 0.962 | |
TNFRSF1A | P19438 | TNF receptor superfamily member 1A | 0.99 | 0.409 | 0.923 | |
RAC1 | P63000 | Rac family small GTPase 1 | Enzyme modulator | 0.76 | 0.429 | 0.962 |
MEFV | O15553 | MEFV innate immuity regulator, pyrin | 1.0E-14 | 0.440 | 0.885 | |
RHOA | P61586 | ras homolog family member A | Enzyme modulator | 0.60 | 0.502 | 0.808 |
SAA1 | P0DJI8 | serum amyloid A1 | Transporter | 1.5E-02 | 0.513 | 0.808 |
ADA2 | Q9NZK5 | adenosine deaminase 2 | Enzyme | 8.1E-08 | 0.545 | 0.846 |
HMGCR | P04035 | 3-hydroxy-3-methylglutaryl-CoA reductase | 1.00 | 0.529 | 0.692 | |
NLRC4 | Q9NPP4 | NLR family CARD domain containing 4 | 9.9E-12 | 0.556 | 0.769 | |
MVK | Q03426 | mevalonate kinase | Kinase | 0.17 | 0.576 | 0.731 |
SEC23B | Q15437 | SEC23 homolog B, COPII coat complex component | Enzyme modulator | 6.1E-20 | 0.579 | 0.692 |
FDFT1 | P37268 | farnesyl-diphosphate farnesyltransferase 1 | 4.1E-15 | 0.621 | 0.615 | |
PSTPIP1 | O43586 | proline-serine-threonine phosphatase interacting protein 1 | Cellular structure | 2.5E-06 | 0.650 | 0.577 |
GRID2 | O43424 | glutamate ionotropic receptor delta type subunit 2 | Ion channel | 1.00 | 0.670 | 0.500 |
MMAB | Q96EY8 | metabolism of cobalamin associated B | Enzyme | 4.1E-03 | 0.695 | 0.538 |
PMVK | Q15126 | phosphomevalonate kinase | 2.7E-05 | 0.769 | 0.308 |