Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
IL2 P60568 interleukin 2 0.48 0.336 0.885
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
H3P10 H3 histone pseudogene 10 0.350 0.846
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923