Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 | |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
STAT3 | P40763 | signal transducer and activator of transcription 3 | Nucleic acid binding | 1.00 | 0.320 | 0.923 |
MMP2 | P08253 | matrix metallopeptidase 2 | Enzyme | 0.84 | 0.333 | 0.923 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
AR | P10275 | androgen receptor | Nuclear receptor | 0.99 | 0.351 | 0.846 |
EGF | P01133 | epidermal growth factor | 8.5E-17 | 0.357 | 0.923 | |
H3P10 | H3 histone pseudogene 10 | 0.350 | 0.846 | |||
MDM2 | Q00987 | MDM2 proto-oncogene | Nucleic acid binding | 1.00 | 0.362 | 0.846 |
VIM | P08670 | vimentin | 0.71 | 0.372 | 0.846 | |
FGF2 | P09038 | fibroblast growth factor 2 | Signaling | 1.8E-02 | 0.383 | 0.923 |
HTC2 | hypertrichosis 2 (generalized, congenital) | 0.392 | 0.808 | |||
CDH1 | P12830 | cadherin 1 | 0.15 | 0.401 | 0.808 | |
HMGA2 | P52926 | high mobility group AT-hook 2 | Nucleic acid binding | 0.87 | 0.429 | 0.808 |
TGFA | P01135 | transforming growth factor alpha | Signaling | 0.72 | 0.432 | 0.885 |
SMN1 | Q16637 | survival of motor neuron 1, telomeric | Epigenetic regulator | 1.6E-02 | 0.454 | 0.769 |
SMN2 | Q16637 | survival of motor neuron 2, centromeric | 0.10 | 0.459 | 0.769 | |
TNFRSF11A | Q9Y6Q6 | TNF receptor superfamily member 11a | 8.8E-03 | 0.480 | 0.846 | |
SRC | P12931 | SRC proto-oncogene, non-receptor tyrosine kinase | Kinase | 1.00 | 0.467 | 0.885 |
FASN | P49327 | fatty acid synthase | Enzyme | 1.00 | 0.474 | 0.846 |
PLAG1 | Q6DJT9 | PLAG1 zinc finger | Transcription factor | 1.00 | 0.493 | 0.808 |