Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 | |
IL1B | P01584 | interleukin 1 beta | 0.13 | 0.276 | 0.962 | |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
CRP | P02741 | C-reactive protein | 3.7E-03 | 0.299 | 0.962 | |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
PTGS2 | P35354 | prostaglandin-endoperoxide synthase 2 | Enzyme | 1.00 | 0.314 | 0.962 |
TLR4 | O00206 | toll like receptor 4 | 4.6E-09 | 0.321 | 0.962 | |
PIK3CD | O00329 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | Kinase | 1.00 | 0.319 | 0.885 |
PIK3CG | P48736 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | Kinase | 1.4E-06 | 0.320 | 0.885 |
PIK3CB | P42338 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta | Kinase | 1.00 | 0.322 | 0.885 |
SMUG1 | Q53HV7 | single-strand-selective monofunctional uracil-DNA glycosylase 1 | 4.5E-04 | 0.322 | 0.923 | |
TLR2 | O60603 | toll like receptor 2 | 1.0E-06 | 0.361 | 0.923 | |
APC | P25054 | APC regulator of WNT signaling pathway | 1.00 | 0.373 | 0.962 | |
PTCH1 | Q13635 | patched 1 | 1.00 | 0.398 | 0.885 | |
SMAD4 | Q13485 | SMAD family member 4 | Transcription factor | 1.00 | 0.401 | 0.808 |
MBL2 | P11226 | mannose binding lectin 2 | Receptor | 2.7E-03 | 0.390 | 0.846 |
HTC2 | hypertrichosis 2 (generalized, congenital) | 0.392 | 0.808 | |||
CDKN1B | P46527 | cyclin dependent kinase inhibitor 1B | 0.62 | 0.409 | 0.769 | |
CASP1 | P29466 | caspase 1 | Enzyme | 3.5E-05 | 0.413 | 0.885 |
BMP2 | P12643 | bone morphogenetic protein 2 | Signaling | 0.99 | 0.432 | 0.846 |
ADA | P00813 | adenosine deaminase | Enzyme | 2.9E-12 | 0.440 | 0.885 |
TGFA | P01135 | transforming growth factor alpha | Signaling | 0.72 | 0.432 | 0.885 |