Disease: Metastatic malignant neoplasm to brain
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
ITGB3 P05106 integrin subunit beta 3 Receptor 1.7E-03 0.485 0.846
CEACAM5 P06731 CEA cell adhesion molecule 5 4.2E-10 0.420 0.846
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
ROS1 P08922 ROS proto-oncogene 1, receptor tyrosine kinase Kinase 1.6E-72 0.439 0.885
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
PSG2 P11465 pregnancy specific beta-1-glycoprotein 2 1.4E-30 0.492 0.731
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808
PTHLH P12272 parathyroid hormone like hormone 0.81 0.453 0.846
CDH1 P12830 cadherin 1 0.15 0.401 0.808
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885
SDC1 P18827 syndecan 1 Extracellular structure 8.4E-03 0.445 0.769
CDH2 P19022 cadherin 2 0.99 0.535 0.731
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
FGFR4 P22455 fibroblast growth factor receptor 4 Kinase 7.2E-13 0.490 0.769