Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
PTGS2 | P35354 | prostaglandin-endoperoxide synthase 2 | Enzyme | 1.00 | 0.314 | 0.962 |
ALB | P02768 | albumin | Transporter | 0.64 | 0.317 | 0.962 |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
MAPK1 | P28482 | mitogen-activated protein kinase 1 | Kinase | 1.00 | 0.330 | 0.923 |
SMUG1 | Q53HV7 | single-strand-selective monofunctional uracil-DNA glycosylase 1 | 4.5E-04 | 0.322 | 0.923 | |
CD274 | Q9NZQ7 | CD274 molecule | Receptor | 1.9E-02 | 0.324 | 0.923 |
COX2 | P00403 | cytochrome c oxidase subunit II | Enzyme | 0.352 | 0.962 | |
SPP1 | P10451 | secreted phosphoprotein 1 | 2.1E-06 | 0.353 | 0.885 | |
TP63 | Q9H3D4 | tumor protein p63 | Transcription factor | 1.00 | 0.362 | 0.769 |
EGF | P01133 | epidermal growth factor | 8.5E-17 | 0.357 | 0.923 | |
MTCO2P12 | MT-CO2 pseudogene 12 | 0.368 | 0.962 | |||
ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 |
EZH2 | Q15910 | enhancer of zeste 2 polycomb repressive complex 2 subunit | Epigenetic regulator | 1.00 | 0.376 | 0.885 |
EPHB2 | P29323 | EPH receptor B2 | Kinase | 1.00 | 0.374 | 0.846 |
CXCL12 | P48061 | C-X-C motif chemokine ligand 12 | 0.12 | 0.379 | 0.846 | |
KDR | P35968 | kinase insert domain receptor | Kinase | 1.00 | 0.378 | 0.885 |
MET | P08581 | MET proto-oncogene, receptor tyrosine kinase | Kinase | 0.97 | 0.380 | 0.846 |
TWIST1 | Q15672 | twist family bHLH transcription factor 1 | Transcription factor | 0.34 | 0.397 | 0.846 |
KRT20 | P35900 | keratin 20 | 9.1E-11 | 0.388 | 0.846 | |
ESR2 | Q92731 | estrogen receptor 2 | Nuclear receptor | 4.5E-08 | 0.400 | 0.923 |