Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
MIR21 | microRNA 21 | 0.363 | 0.846 | |||
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
CHEK2 | O96017 | checkpoint kinase 2 | Kinase | 1.2E-24 | 0.460 | 0.808 |
PALB2 | Q86YC2 | partner and localizer of BRCA2 | 3.0E-19 | 0.485 | 0.769 | |
CYP1A1 | P04798 | cytochrome P450 family 1 subfamily A member 1 | Enzyme | 1.1E-17 | 0.436 | 0.846 |
BRIP1 | Q9BX63 | BRCA1 interacting protein C-terminal helicase 1 | Enzyme | 6.2E-17 | 0.507 | 0.731 |
EPCAM | P16422 | epithelial cell adhesion molecule | 1.3E-07 | 0.451 | 0.885 | |
PRL | P01236 | prolactin | Signaling | 2.9E-07 | 0.406 | 0.885 |
CASP8 | Q14790 | caspase 8 | Enzyme | 3.7E-06 | 0.404 | 0.923 |
ABCB1 | P08183 | ATP binding cassette subfamily B member 1 | Transporter | 1.3E-05 | 0.344 | 0.885 |
CYP19A1 | P11511 | cytochrome P450 family 19 subfamily A member 1 | Enzyme | 1.7E-05 | 0.410 | 0.885 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
CAV1 | Q03135 | caveolin 1 | Enzyme modulator | 8.3E-03 | 0.388 | 0.885 |
HRAS | P01112 | HRas proto-oncogene, GTPase | Enzyme modulator | 8.0E-02 | 0.378 | 0.885 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
CXCL10 | P02778 | C-X-C motif chemokine ligand 10 | Signaling | 0.37 | 0.378 | 0.885 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
PDLIM7 | Q9NR12 | PDZ and LIM domain 7 | Cellular structure | 0.71 | 0.474 | 0.808 |
HIF1A | Q16665 | hypoxia inducible factor 1 subunit alpha | Transcription factor | 0.98 | 0.327 | 0.923 |
AR | P10275 | androgen receptor | Nuclear receptor | 0.99 | 0.351 | 0.846 |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |