Disease: Steroid Sulfatase Deficiency Disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808
PSC Cholangitis, primary sclerosing 0.603 0.731
CHEK1 O14757 checkpoint kinase 1 Kinase 3.1E-08 0.492 0.808
MDM4 O15151 MDM4 regulator of p53 Nucleic acid binding 1.00 0.461 0.808
HPGDS O60760 hematopoietic prostaglandin D synthase 1.8E-06 0.388 0.923
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885
GADD45A P24522 growth arrest and DNA damage inducible alpha 4.4E-02 0.526 0.769
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808