Disease: FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder)
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CHEK1 O14757 checkpoint kinase 1 Kinase 3.1E-08 0.492 0.808
BACH1 O14867 BTB domain and CNC homolog 1 0.57 0.585 0.731
PPM1D O15297 protein phosphatase, Mg2+/Mn2+ dependent 1D Enzyme 2.2E-11 0.513 0.808
RAD51B O15315 RAD51 paralog B 2.1E-15 0.556 0.769
FANCA O15360 FA complementation group A 1.6E-68 0.505 0.731
RAD51C O43502 RAD51 paralog C 6.2E-14 0.533 0.692
XRCC3 O43542 X-ray repair cross complementing 3 1.9E-10 0.505 0.769
XRCC2 O43543 X-ray repair cross complementing 2 4.0E-07 0.512 0.731
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
HPGDS O60760 hematopoietic prostaglandin D synthase 1.8E-06 0.388 0.923
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808
RAD51D O75771 RAD51 paralog D 1.1E-09 0.674 0.385
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
CDH1 P12830 cadherin 1 0.15 0.401 0.808
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885
MSH3 P20585 mutS homolog 3 Nucleic acid binding 7.4E-31 0.474 0.769
TTK P33981 TTK protein kinase Kinase 1.3E-03 0.555 0.731
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885