| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
|---|---|---|---|---|---|---|
| APC | P25054 | APC regulator of WNT signaling pathway | 1.00 | 0.373 | 0.962 | |
| AR | P10275 | androgen receptor | Nuclear receptor | 0.99 | 0.351 | 0.846 |
| ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 |
| BARD1 | Q99728 | BRCA1 associated RING domain 1 | 1.4E-24 | 0.597 | 0.538 | |
| BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
| BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
| BRCA3 | breast cancer 3 | 0.705 | 0.269 | |||
| CHEK2 | O96017 | checkpoint kinase 2 | Kinase | 1.2E-24 | 0.460 | 0.808 |
| CYP19A1 | P11511 | cytochrome P450 family 19 subfamily A member 1 | Enzyme | 1.7E-05 | 0.410 | 0.885 |
| ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
| ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
| GEN1 | Q17RS7 | GEN1 Holliday junction 5' flap endonuclease | 3.7E-15 | 0.682 | 0.500 | |
| HTC2 | hypertrichosis 2 (generalized, congenital) | 0.392 | 0.808 | |||
| NBN | O60934 | nibrin | Nucleic acid binding | 2.2E-16 | 0.467 | 0.808 |
| NLRP2 | Q9NX02 | NLR family pyrin domain containing 2 | 1.4E-38 | 0.515 | 0.731 | |
| PALB2 | Q86YC2 | partner and localizer of BRCA2 | 3.0E-19 | 0.485 | 0.769 | |
| PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
| RAD51 | Q06609 | RAD51 recombinase | 2.7E-02 | 0.447 | 0.846 | |
| RAD51C | O43502 | RAD51 paralog C | 6.2E-14 | 0.533 | 0.692 | |
| SLX4 | Q8IY92 | SLX4 structure-specific endonuclease subunit | 1.6E-22 | 0.565 | 0.731 | |
| TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |