Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
MRC1 P22897 mannose receptor C-type 1 0.94 0.413 0.846
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885
PGR P06401 progesterone receptor Nuclear receptor 5.1E-02 0.426 0.885
IGFBP3 P17936 insulin like growth factor binding protein 3 Enzyme modulator 0.91 0.439 0.808
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
HNF1B P35680 HNF1 homeobox B Nucleic acid binding 1.00 0.473 0.808
CDX2 Q99626 caudal type homeobox 2 Transcription factor 0.53 0.458 0.769