Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
FGFR2 | P21802 | fibroblast growth factor receptor 2 | Kinase | 1.00 | 0.380 | 0.808 |
MLH1 | P40692 | mutL homolog 1 | Nucleic acid binding | 3.4E-05 | 0.399 | 0.808 |
MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |
ATR | Q13535 | ATR serine/threonine kinase | Kinase | 3.5E-09 | 0.456 | 0.923 |
MSH6 | P52701 | mutS homolog 6 | Nucleic acid binding | 3.7E-05 | 0.462 | 0.731 |
CUX1 | P39880 Q13948 | cut like homeobox 1 | Transcription factor | 1.00 | 0.465 | 0.846 |
FBXW7 | Q969H0 | F-box and WD repeat domain containing 7 | Enzyme modulator | 1.00 | 0.465 | 0.808 |
PMS2 | P54278 | PMS1 homolog 2, mismatch repair system component | Nucleic acid binding | 4.5E-27 | 0.484 | 0.808 |
RAD21 | O60216 | RAD21 cohesin complex component | 1.00 | 0.528 | 0.846 | |
POLE | Q07864 | DNA polymerase epsilon, catalytic subunit | 8.0E-27 | 0.526 | 0.731 | |
MAX | P61244 | MYC associated factor X | Transcription factor | 0.83 | 0.553 | 0.769 |
PIK3R2 | O00459 | phosphoinositide-3-kinase regulatory subunit 2 | Enzyme modulator | 1.6E-02 | 0.551 | 0.808 |
AXIN1 | O15169 | axin 1 | 0.41 | 0.559 | 0.577 | |
PMS1 | P54277 | PMS1 homolog 1, mismatch repair system component | Nucleic acid binding | 1.3E-17 | 0.569 | 0.654 |
SPOP | O43791 | speckle type BTB/POZ protein | 1.00 | 0.597 | 0.500 |