Disease: HER2-positive carcinoma of breast
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AK4 P27144 adenylate kinase 4 Kinase 0.13 0.705 0.462
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
BCAR1 P56945 BCAR1 scaffold protein, Cas family member 1.00 0.518 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
CDKN2B-AS1 CDKN2B antisense RNA 1 0.491 0.769
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
CUL3 Q13618 cullin 3 1.00 0.592 0.654
E2F1 Q01094 E2F transcription factor 1 Nucleic acid binding 0.99 0.441 0.846
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
EPHA2 P29317 EPH receptor A2 Kinase 1.1E-05 0.501 0.731
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
FEN1 P39748 flap structure-specific endonuclease 1 Enzyme 4.8E-05 0.550 0.731
FOXM1 Q08050 forkhead box M1 7.4E-04 0.441 0.769
GAS5 growth arrest specific 5 0.497 0.808
HDAC9 Q9UKV0 histone deacetylase 9 Epigenetic regulator 1.00 0.439 0.846
HSF1 Q00613 heat shock transcription factor 1 Transcription factor 0.75 0.507 0.769
HSP90AA1 P07900 heat shock protein 90 alpha family class A member 1 Chaperone 0.86 0.411 0.923
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
MALAT1 metastasis associated lung adenocarcinoma transcript 1 0.435 0.846
MAP2K7 O14733 mitogen-activated protein kinase kinase 7 Kinase 1.00 0.419 0.808
MCL1 Q07820 MCL1 apoptosis regulator, BCL2 family member Signaling 0.96 0.430 0.808