Disease: Achondroplasia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CYP2C19 P33261 cytochrome P450 family 2 subfamily C member 19 6.5E-20 0.467 0.846
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923
SNAI1 O95863 snail family transcriptional repressor 1 0.22 0.474 0.808
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
DCN P07585 decorin 0.31 0.457 0.808
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
PTHLH P12272 parathyroid hormone like hormone 0.81 0.453 0.846
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
GRB10 Q13322 growth factor receptor bound protein 10 Receptor 0.94 0.628 0.615
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
STAT5B P51692 signal transducer and activator of transcription 5B Nucleic acid binding 1.00 0.442 0.808
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885
HDAC6 Q9UBN7 histone deacetylase 6 Epigenetic regulator 1.00 0.465 0.846
ARID1B Q8NFD5 AT-rich interaction domain 1B 1.00 0.503 0.846