| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
|---|---|---|---|---|---|---|
| TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
| CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
| KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
| BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
| APC | P25054 | APC regulator of WNT signaling pathway | 1.00 | 0.373 | 0.962 | |
| BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
| SMAD4 | Q13485 | SMAD family member 4 | Transcription factor | 1.00 | 0.401 | 0.808 |
| STK11 | Q15831 | serine/threonine kinase 11 | Kinase | 0.99 | 0.435 | 0.808 |
| EP300 | Q09472 | E1A binding protein p300 | 1.00 | 0.459 | 0.846 | |
| AKT2 | P31751 | AKT serine/threonine kinase 2 | Kinase | 0.64 | 0.474 | 0.769 |
| RBBP8 | Q99708 | RB binding protein 8, endonuclease | Transcription factor | 3.1E-12 | 0.584 | 0.808 |
| MAP2K4 | P45985 | mitogen-activated protein kinase kinase 4 | Kinase | 1.00 | 0.559 | 0.692 |
| RNF43 | Q68DV7 | ring finger protein 43 | 0.73 | 0.584 | 0.577 |