Source: CLINVAR ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
WDR6 Q9NNW5 WD repeat domain 6 2.1E-09
H2AP O75409 H2A.P histone Nucleic acid binding
ITIH6 Q6UXX5 inter-alpha-trypsin inhibitor heavy chain family member 6 1.5E-24
KCND1 Q9NSA2 potassium voltage-gated channel subfamily D member 1 Ion channel 0.26
DPRX A6NFQ7 divergent-paired related homeobox 2.4E-06
ZNF446 Q9NWS9 zinc finger protein 446 5.7E-08
CEP76 Q8TAP6 centrosomal protein 76 4.5E-09
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
PTCH1 Q13635 patched 1 1.00 0.398 0.885
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
DMD P11532 dystrophin 1.00 0.423 0.923
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
ROS1 P08922 ROS proto-oncogene 1, receptor tyrosine kinase Kinase 1.6E-72 0.439 0.885
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846
STAT5B P51692 signal transducer and activator of transcription 5B Nucleic acid binding 1.00 0.442 0.808
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846