Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
COX8A P10176 cytochrome c oxidase subunit 8A Enzyme 0.12 0.400 0.846
TBC1D9 Q6ZT07 TBC1 domain family member 9 Enzyme 2.8E-05 0.399 0.846
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
SMARCB1 Q12824 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Nucleic acid binding 1.00 0.434 0.846
TYMS P04818 thymidylate synthetase Enzyme 0.72 0.425 0.846
PECAM1 P16284 platelet and endothelial cell adhesion molecule 1 Cell adhesion 0.426 0.846
PGR P06401 progesterone receptor Nuclear receptor 5.1E-02 0.426 0.885
CST3 P01034 cystatin C 3.9E-03 0.436 0.808
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808
NF2 P35240 neurofibromin 2 1.00 0.468 0.885
PDGFB P01127 platelet derived growth factor subunit B Signaling 0.77 0.488 0.846
BAP1 Q92560 BRCA1 associated protein 1 Enzyme 0.99 0.454 0.731
CASP9 P55211 caspase 9 Enzyme 7.4E-06 0.458 0.808
SUFU Q9UMX1 SUFU negative regulator of hedgehog signaling 1.00 0.493 0.769